Comparative genomic analysis of filoviruses using GLUE
Welcome to Filovirus-GLUE, a resource for comparative genomic analysis of filoviruses (family Filoviridae), developed using the GLUE software framework.
The Filoviridae comprise enveloped, negative-sense RNA viruses, many of which pose serious risks to human health.
GLUE is an open, integrated software toolkit designed for storing and interpreting sequence data. It supports the creation of bespoke projects, incorporating essential data items for comparative genomic analysis, such as sequences, multiple sequence alignments, genome feature annotations, and other associated data.
Projects are loaded into the GLUE "engine," forming a relational database that represents the semantic relationships between data items. This foundation supports systematic comparative analyses and the development of sequence-based resources.
Filovirus-GLUE contains genome feature definitions, multiple sequence alignments, and annotated reference sequences for all filovirus species included in the most recent ICTV report.
This Filovirus-GLUE project can be extended with additional layers, openly available via GitHub, including Filovirus-GLUE-EVE which extends Filovirus-GLUE through the incorporation of endogenous filoviral elements.
License
This project is licensed under the GNU Affero General Public License v. 3.0.